TP508

Healing & repair In trials Human trials

Also called Chrysalin, Rusalatide acetate

A 23-amino-acid peptide copied from a non-clotting region of human thrombin. It signals blood vessel lining cells and stem cells to start repair, improving blood supply at injury sites. It has been tested for diabetic foot ulcers, fracture healing and radiation injury.

Evidence at a glance

Evidence: Human trials — Studied in people
Status: Reached clinical trials
Dosing: No human study has set a dose

Later trials did not clearly confirm the early results and development stalled.

What studies report

Faster closure of diabetic foot ulcers in phase 2
Faster fracture healing signals in a distal radius trial
Protection against radiation injury in animals

How it works

A fragment of thrombin that keeps the repair signalling without the clotting. It binds receptors on blood vessel lining and stem cells, restoring blood flow and recruiting repair cells to an injury.

Binds a receptor on the cell surface and signals inward

Where it acts

Joints & cartilage

The library groups this compound under Healing & repair. The diagram shows that target, not every tissue it reaches.

Illustrated

Dermal connective tissue with normal collagen bundles and a fine microvascular network.

AI-generated subject illustration; not a depiction of the compound or evidence of its effects.

Why people take it

Wound and fracture healingDiabetic foot ulcersBlood flow at injury sites

Reasons people seek it out — not a list of proven effects.

In practice Unapproved use

Rarely available; occasional use for stubborn wounds

Reported real-world use, not evidence and not a recommendation.

Status: Reached phase 2/3 trials for wounds and fractures. Not approved.

Route: Subcutaneous injection, from reconstituted lyophilised powder
Sequence: AGYKPDEGKRGDACEGDSGGPFV
Formula: C97H146N28O36S
Molecular weight: 2312.4 g/mol
CAS: 121341-81-9
Available as: 5 mg

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Educational information only. Nothing here is medical advice, a dosing protocol, or a recommendation to use any compound. Most entries describe substances not approved for human use. Talk to a licensed clinician before acting on anything you read here. How to read these entries.