N-Acetyl Semax Amidate
Cognitive & neuro Research only Animal studies
Also called NA-Semax Amidate, Ac-MEHFPGP-NH2
Semax with protective caps on both ends — an acetyl group at one end, an amide at the other. The caps slow the enzymes that would otherwise chew it up, which is intended to extend how long it lasts, particularly when given nasally.
Evidence at a glance
- Evidence
- Animal studies — Not yet studied in people
- Status
- Research compound only
- Dosing
- No human study has set a dose
The capped form has far less direct research behind it than Semax itself — most claims are inferred from the parent peptide rather than demonstrated for this version.
What studies report
- Shares the seven-residue core of Semax, which raises BDNF in the brain
- Terminal capping slows breakdown by exopeptidases in lab assays
How it works
Same seven-residue core as Semax, raising BDNF in the brain, with terminal caps added to resist the exopeptidases that clear the parent peptide quickly.
Where it acts
BrainThe library groups this compound under Cognitive & neuro. The diagram shows that target, not every tissue it reaches.
Illustrated
AI-generated subject illustration; not a depiction of the compound or evidence of its effects.
Why people take it
Reasons people seek it out — not a list of proven effects.
In practice Unapproved use
- Preferred by users who find plain Semax too short-acting
Reported real-world use, not evidence and not a recommendation.
Status: Research compound. Not approved.
- Route
- Intranasal spray
- Sequence
- Ac-Met-Glu-His-Phe-Pro-Gly-Pro-NH2
- Formula
- C39H54N10O10S
- Molecular weight
- 855.0 g/mol
- CAS
- 2920938-90-3
- Available as
- 20 mg
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Educational information only. Nothing here is medical advice, a dosing protocol, or a recommendation to use any compound. Most entries describe substances not approved for human use. Talk to a licensed clinician before acting on anything you read here. How to read these entries.