IRW peptide

Cardiovascular Research only Animal studies

Also called Ile-Arg-Trp

A three-amino-acid peptide first identified in egg white protein (ovotransferrin). It inhibits ACE and raises ACE2, two enzymes with opposing roles in blood pressure control. In hypertensive rats it lowered blood pressure and reduced vascular inflammation.

Evidence at a glance

Evidence
Animal studies — Not yet studied in people
Status
Research compound only
Dosing
No human study has set a dose

Animal only, and derived from a food protein studied mostly as a dietary ingredient.

What studies report

How it works

Inhibits ACE while raising ACE2, two enzymes with opposing effects on blood pressure. Shifting the balance toward ACE2 reduces angiotensin II and the vascular inflammation that follows it.

Binds a receptor on the cell surface and signals inward

Where it acts

Acts in blood vessels, throughout the body

The library groups this compound under Cardiovascular. The diagram shows that target, not every tissue it reaches.

Illustrated

Endothelial cells lining an arterial lumen with a few red cells, longitudinal internal vessel view.

AI-generated subject illustration; not a depiction of the compound or evidence of its effects.

Why people take it

Blood pressureVascular inflammation

Reasons people seek it out — not a list of proven effects.

Status: Animal and cell research only.

Route
Oral — absorbed intact, unusually for a peptide
Sequence
Ile-Arg-Trp
Formula
C23H35N7O4
Molecular weight
473.6 g/mol
Available as
10 mg

Search PubMed for IRW peptide → We link a live search rather than a fixed citation list, so it stays current and nothing here is a reference we have not checked.

Educational information only. Nothing here is medical advice, a dosing protocol, or a recommendation to use any compound. Most entries describe substances not approved for human use. Talk to a licensed clinician before acting on anything you read here. How to read these entries.