FGL

Cognitive & neuro Research only Human trials

Also called FG loop peptide, NCAM mimetic

A 15-amino-acid peptide copied from the neural cell adhesion molecule (NCAM). It activates the FGF receptor, which encourages neurons to grow new branches and strengthens synapses. In rodents it improved learning and memory and protected neurons after injury.

Evidence at a glance

Evidence: Human trials — Studied in people
Status: Research compound only
Dosing: No human study has set a dose

No human efficacy data.

What studies report

Better spatial learning and memory in aged and injured rats
Reduced neuron loss after brain injury in animals
Safe and well tolerated in one phase 1 human study

How it works

Copies the FG loop of the neural cell adhesion molecule and activates the FGF receptor, which tells neurons to extend new branches and strengthens the synapses between them.

Binds a receptor on the cell surface and signals inward

Where it acts

Brain

The library groups this compound under Cognitive & neuro. The diagram shows that target, not every tissue it reaches.

Illustrated

A neuronal growth cone with delicate filopodia extending across a neutral cellular substrate.

AI-generated subject illustration; not a depiction of the compound or evidence of its effects.

Why people take it

Memory and learningNeuron protection after injury

Reasons people seek it out — not a list of proven effects.

Status: Animal research, with one small early human safety study.

Route: Subcutaneous injection, from reconstituted lyophilised powder
Sequence: EVYVVAENQQGKSKA
Available as: 10 mg

Search PubMed for FGL → We link a live search rather than a fixed citation list, so it stays current and nothing here is a reference we have not checked.

Educational information only. Nothing here is medical advice, a dosing protocol, or a recommendation to use any compound. Most entries describe substances not approved for human use. Talk to a licensed clinician before acting on anything you read here. How to read these entries.