Thymogen
Thymus & immune system Approved · Russia Human trials Synthetic short peptide (Cytogen)
Also called Thymagen, Oglufanide, EW dipeptide
A two-amino-acid peptide first isolated from calf thymus extract and now made synthetically. It is the most clinically used of this family, given to support immune recovery during infections and after surgery or radiation.
Evidence at a glance
- Evidence
- Human trials — Studied in people
- Status
- An approved medicine in Russia
- Dosing
- No human study has set a dose
The most clinically used of this family, but the trials are Russian and mostly older.
What studies report
- Used clinically in Russia to support immune recovery during infection and after surgery or radiation
- Studied in hepatitis B and C
How it works
A Khavinson short peptide: at two to four amino acids it is small enough to pass through cell and nuclear membranes intact. The proposed mechanism is that it binds specific sites on nuclear DNA and changes which genes are switched on in its target tissue, rather than acting on a surface receptor the way most peptides do.
Where it acts
ThymusThe library groups this compound under Thymus & immune system. The diagram shows that target, not every tissue it reaches.
Illustrated

AI-generated subject illustration; not a depiction of the compound or evidence of its effects.
Why people take it
Reasons people seek it out — not a list of proven effects.
Status: Registered medicine in Russia. Not approved in the US or EU.
- Route
- Subcutaneous injection, or oral capsule depending on the preparation
- Sequence
- Glu-Trp
- Formula
- C16H19N3O5
- Molecular weight
- 333.34 g/mol
- CAS
- 38101-59-6
- Available as
- 1 mg
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Compared with
Side-by-side pages for the compounds this one is most often confused with or taken alongside.
Educational information only. Nothing here is medical advice, a dosing protocol, or a recommendation to use any compound. Most entries describe substances not approved for human use. Talk to a licensed clinician before acting on anything you read here. How to read these entries.