Thymogen

Thymus & immune system Approved · Russia Human trials Synthetic short peptide (Cytogen)

Also called Thymagen, Oglufanide, EW dipeptide

A two-amino-acid peptide first isolated from calf thymus extract and now made synthetically. It is the most clinically used of this family, given to support immune recovery during infections and after surgery or radiation.

Evidence at a glance

Evidence
Human trials — Studied in people
Status
An approved medicine in Russia
Dosing
No human study has set a dose

The most clinically used of this family, but the trials are Russian and mostly older.

What studies report

How it works

A Khavinson short peptide: at two to four amino acids it is small enough to pass through cell and nuclear membranes intact. The proposed mechanism is that it binds specific sites on nuclear DNA and changes which genes are switched on in its target tissue, rather than acting on a surface receptor the way most peptides do.

Small enough to pass through and act on DNA in the nucleus

Where it acts

Thymus

The library groups this compound under Thymus & immune system. The diagram shows that target, not every tissue it reaches.

Illustrated

AI-generated subject illustration; not a depiction of the compound or evidence of its effects.

Why people take it

Immune recovery during infectionPost-surgical recoveryHepatitis support

Reasons people seek it out — not a list of proven effects.

Status: Registered medicine in Russia. Not approved in the US or EU.

Route
Subcutaneous injection, or oral capsule depending on the preparation
Sequence
Glu-Trp
Formula
C16H19N3O5
Molecular weight
333.34 g/mol
CAS
38101-59-6
Available as
1 mg
View on PubChem →

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Compared with

Side-by-side pages for the compounds this one is most often confused with or taken alongside.

Educational information only. Nothing here is medical advice, a dosing protocol, or a recommendation to use any compound. Most entries describe substances not approved for human use. Talk to a licensed clinician before acting on anything you read here. How to read these entries.