Selank
Cognitive & neuro Approved · Russia Human trials
A seven-amino-acid peptide developed in Russia from tuftsin, a natural immune peptide, with three amino acids added for stability. It is studied for calming anxiety without sedation and for effects on memory, GABA signaling, BDNF and immune messengers.
Evidence at a glance
- Evidence
- Human trials — Studied in people
- Status
- An approved medicine in Russia
- Dosing
- A dose has been tested in humans
Trials are Russian, small, and not independently replicated.
What studies report
- Anxiety reduction comparable to a benzodiazepine in Russian trials, without sedation or dependence
- Improved attention and memory measures
- Effects on BDNF, GABA and serotonin signalling
How it works
A synthetic analogue of tuftsin with four extra residues for stability. It influences GABA and monoamine signalling and raises BDNF, which is the proposed route to anxiety reduction without sedation.
Where it acts
BrainThe library groups this compound under Cognitive & neuro. The diagram shows that target, not every tissue it reaches.
Illustrated
AI-generated subject illustration; not a depiction of the compound or evidence of its effects.
Why people take it
Reasons people seek it out — not a list of proven effects.
In practice Off-label
- Used as a nasal spray situationally for anxiety, where a benzodiazepine would sedate
- Often paired with Semax, one for calm and one for drive
Reported real-world use, not evidence and not a recommendation.
Dosing
What was tested Evidence
- Intranasal, daily over 14 daysRussian generalised anxiety trials→ Anxiety reduction comparable to benzodiazepines, without sedation
What people report using Not evidence
- Used situationally rather than daily
- Often paired with Semax
Reported for reference, not as instruction. Nothing here is a recommendation to take anything, and most of these compounds are not approved for human use.
Status: Approved in Russia as a nasal anti-anxiety medicine. Not approved elsewhere.
- Route
- Intranasal spray
- Sequence
- Thr-Lys-Pro-Arg-Pro-Gly-Pro
- Formula
- C33H57N11O9
- Molecular weight
- 751.9 g/mol
- CAS
- 129954-34-3
- Available as
- 10 mg
Search PubMed for Selank → We link a live search rather than a fixed citation list, so it stays current and nothing here is a reference we have not checked.
Compared with
Side-by-side pages for the compounds this one is most often confused with or taken alongside.
Educational information only. Nothing here is medical advice, a dosing protocol, or a recommendation to use any compound. Most entries describe substances not approved for human use. Talk to a licensed clinician before acting on anything you read here. How to read these entries.