GHRP-6

Growth hormone Research only Human trials

Also called Growth hormone releasing peptide 6, SK&F 110679, Hexapeptide-2

A six-amino-acid peptide that activates the ghrelin receptor to release growth hormone. It is the hungriest of the GHRP family — the appetite stimulation is pronounced, which is the main thing separating it from GHRP-2 and ipamorelin.

Evidence at a glance

Evidence: Human trials — Studied in people
Status: Research compound only
Dosing: No human study has set a dose

Also raises cortisol and prolactin, and the hunger is strong enough that many find it unworkable. Studied for hormone response, not for outcomes like body composition.

What studies report

Reliable growth hormone release in human pharmacology studies
Strong appetite stimulation through ghrelin receptor activity
Protective effects on the stomach lining in animal studies

How it works

Activates the same ghrelin receptor as the other GHRPs, but with the strongest appetite effect of the family — the hunger is the mechanism working, not a side effect.

Binds a receptor on the cell surface and signals inward

Where it acts

Pituitary gland

The library groups this compound under Growth hormone. The diagram shows that target, not every tissue it reaches.

Illustrated

Human stomach endocrine mucosal tissue with small secretory cells in glandular folds, macro view.

AI-generated subject illustration; not a depiction of the compound or evidence of its effects.

Why people take it

Growth hormone releaseAppetite stimulation and weight gainRecovery and healingGut lining protection

Reasons people seek it out — not a list of proven effects.

In practice Unapproved use

Deliberately used by people trying to gain weight, for the hunger
Generally avoided during fat loss phases for the same reason

Reported real-world use, not evidence and not a recommendation.

Status: Research compound. Not approved.

Route: Subcutaneous injection, from reconstituted lyophilised powder
Sequence: His-D-Trp-Ala-Trp-D-Phe-Lys-NH2
Formula: C46H56N12O6
Molecular weight: 873.0 g/mol
CAS: 87616-84-0
Available as: 10 mg

View on PubChem →

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Educational information only. Nothing here is medical advice, a dosing protocol, or a recommendation to use any compound. Most entries describe substances not approved for human use. Talk to a licensed clinician before acting on anything you read here. How to read these entries.