BPC-157

Healing & repair Research only Animal studies

Also called Body Protection Compound 157

A 15-amino-acid synthetic peptide based on a protein fragment found in stomach juice. In animal studies it has been linked to faster healing of tendon, muscle, gut and skin injuries, new blood vessel growth, and effects on nitric oxide signaling.

Evidence at a glance

Evidence: Animal studies — Not yet studied in people
Status: Research compound only
Dosing: No human study has set a dose

Essentially all of this is rodent data. There are no published controlled human trials, and claims about joint or gut healing in people are extrapolation.

What studies report

Faster tendon, ligament and muscle healing in rat injury models
Protection of the stomach and gut lining against NSAID and alcohol damage in rodents
New blood vessel growth at injury sites in animals

How it works

Derived from a protein in gastric juice. Reported to upregulate growth hormone receptors via the phospholipase C pathway and to drive angiogenesis — new blood vessel growth into damaged tissue.

Binds a receptor on the cell surface and signals inward

Where it acts

Joints & cartilage

The library groups this compound under Healing & repair. The diagram shows that target, not every tissue it reaches.

Illustrated

Human skeletal muscle fibres joining a collagen tendon.

AI-generated subject illustration; not a depiction of the compound or evidence of its effects.

Why people take it

Achilles and other tendon tearsACL and meniscus injuryRotator cuff tearsIT band syndromeGut lining, GERD and ulcersTendon, ligament and muscle injury

Reasons people seek it out — not a list of proven effects.

In practice Unapproved use

Among the most widely used peptides in the injury-recovery community, usually run in 4–8 week blocks
Commonly injected near the injury site for tendon and ligament problems, or systemically
Oral and capsule forms are preferred for gut complaints, since it originates in the digestive tract
Routinely stacked with TB-500 — the pairing is common enough to have its own nickname
Sold pre-blended with thymosin-β4 as a “Wolverine stack”, and in four-way GHK and KPV blends, so buyers often take several peptides without measuring any of them separately

Science hasn't caught up: This is the widest practice-versus-evidence gap in the library: near-universal adoption in recovery circles, zero published controlled human trials.

Reported real-world use, not evidence and not a recommendation.

Dosing

No human study has established a dose for this compound.

What people report using Not evidence

250–500 mcg daily, subcutaneous, is the most commonly cited range
Often injected near the injury site for tendon and ligament work
Run in 4–8 week blocks
Oral capsules used instead for gut complaints

There are no published human trials, so there is no studied dose at all — every figure here comes from community practice.

Reported for reference, not as instruction. Nothing here is a recommendation to take anything, and most of these compounds are not approved for human use.

Status: Evidence is almost entirely from animal and cell studies. Human data are very limited. Not approved.

Route: Subcutaneous injection; oral and capsule forms are used for gut complaints; also sold as a ready-made intranasal spray
Sequence: Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val
Formula: C62H98N16O22
Molecular weight: 1419.5 g/mol
CAS: 137525-51-0
Available as: 10 mg

View on PubChem →

Search PubMed for BPC-157 → We link a live search rather than a fixed citation list, so it stays current and nothing here is a reference we have not checked.

Compared with

vs Thymosin-β4 →vs KPV →

Side-by-side pages for the compounds this one is most often confused with or taken alongside.

Educational information only. Nothing here is medical advice, a dosing protocol, or a recommendation to use any compound. Most entries describe substances not approved for human use. Talk to a licensed clinician before acting on anything you read here. How to read these entries.