ATX-GD-59

Immune In trials Human trials

A mix of two short peptides copied from the thyroid-stimulating hormone receptor. The idea is to retrain the immune system to tolerate that receptor, so it stops making the antibodies that drive Graves' disease, instead of suppressing immunity overall.

Evidence at a glance

Evidence
Human trials — Studied in people
Status
Reached clinical trials
Dosing
No human study has set a dose

One small open-label study in 12 people; no control group.

What studies report

How it works

Two short fragments of the TSH receptor given to retrain immune tolerance. Presenting the target antigen in this form is meant to stop the immune system attacking the thyroid, rather than suppressing immunity generally.

Binds a receptor on the cell surface and signals inward

Where it acts

Thymus

The library groups this compound under Immune. The diagram shows that target, not every tissue it reaches.

Illustrated

AI-generated subject illustration; not a depiction of the compound or evidence of its effects.

Why people take it

Graves' disease and thyroid autoimmunity

Reasons people seek it out — not a list of proven effects.

Status: Early (phase 1) human study only. Not approved.

Route
Subcutaneous injection, from reconstituted lyophilised powder
Available as
1.6 mg

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Educational information only. Nothing here is medical advice, a dosing protocol, or a recommendation to use any compound. Most entries describe substances not approved for human use. Talk to a licensed clinician before acting on anything you read here. How to read these entries.